Four Penn Neurology recipients of R25 research supplements


The R25 Research Education Program supports research activities during clinical neuroscience training. Residents may submit an application in October of their senior resident year. Recipients of the grant receive extra flexibility in scheduling research time during residency, and have the option of applying for additional years of research support during Fellowship.

This year, all four of our applicants from the Penn Neurology department received the R25 supplement. The four recipients and their projects are:

Ana G. Cristancho -- Pediatric Neurology Resident

Dr. Christancho will be working with Stewart A. Anderson MD, PhD and Eric D. Marsh, MD on a project entitled “Mitochondria, hypoxia, and cortical interneuron development - a putative gene-environment interaction in the pathogenesis of neurodevelopmental disease.” This project seeks to determine the contribution of mitochondrial dysfunction from intrauterine hypoxic injury on interneuron migration.



Eric A. Kaiser -- Adult Neurology Resident

Dr. Kaiser will be working with Geoffrey K. Aguirre MD, PhD on a project entitled “Photoreceptor- specific mechanisms of migraine-associated photophobia.” This project will investigate the selective contribution of cone and melanopsin stimulation to the symptom of photophobia, which is a major source of morbidity in migraine.




Armina Omole -- Adult Neurology Resident

Dr. Omole will be working with Douglas Smith, MD and Frances Jensen, MD on a project entitled “Progressive neuropathological mechanisms of post traumatic epileptogenesis.” This project will investigate the neuropathological correlates of post traumatic epilepsy in a rat lateral fluid percussion model of traumatic brain injury, and will include EEG monitoring for high frequency oscillations and seizures.


Christopher Favilla -- Adult Neurology Vascular Fellow

Dr. Favilla will be working with John Detre, MD and Dr. Steven Mess√©, MD on a project entitled “Effects of Intrathoracic Pressure on Cerebral Blood Flow in Stroke.” This project leverages a novel technology for transcranial optical monitoring of cerebral blood flow. Dr. Favilla will use this technology to assess the effects of intrathoracic pressure modulation on CBF and its potential use in acute stroke management.

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Contact Information

Department of Neurology
3 Gates, Hospital of the University of Pennsylvania
3400 Spruce Street
Philadelphia, PA 19104

Frances E. Jensen, MD, FACP
Chair of Neurology

Raymond S. Price, MD
Program Director

Vanna Hing, Residency Coordinator

Telephone: (215) 662-3370
vanna.hing@uphs.upenn.edu